Skin of Body

Taxonomy

• Homo sapiens (Human)

Protein

• Low-density lipoprotein receptor / Homo sapiens    P01130
• Tissue-type plasminogen activator / Homo sapiens    P00750

Source

• Skin of Body (UBERON_0002097)   A-431 (CVCL_0037)   Fibroblast (CL_0000057)  
• Skin of Body (UBERON_0002097)   HMCB (CVCL_3317)  

Reported structure

• O-Linked / Core 0 / GalNAc
• O-Linked / O-Fuc / Fuc

Composition

• dHex:1 (avg mass : 164.1583 )
• HexNAc:1 (avg mass : 221.2103 )

Disease

• Carcinoma, Squamous cell (DOID:1749)
• Melanoma (DOID:1909)

Reference

• Tissue plasminogen activator has an O-linked fucose attached to threonine-61 in the epidermal growth factor domain. (1991 - Harris R, Leonard C, Guzzetta A, Spellman M) / Status : Reviewed
• Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor. (1983 - Cummings R, Kornfeld S, Schneider W, Hobgood K, Tolleshaug H, Brown M, Goldstein J) / Status : Reviewed

Reported glycosite

• Low-density lipoprotein receptor / Homo sapiens
  •        Undefined site
• Tissue-type plasminogen activator / Homo sapiens
  •        Thr-96

Mass spectrometry observed peptide