Liver

Taxonomy

• Homo sapiens (Human)
• Rattus norvegicus (Norway rat)

Protein

• Thrombospondin-1 / Homo sapiens    P07996
• Amino acid fucoside - fl3 / Rattus norvegicus    
• Nuclear pore glycoprotein p62 / Rattus norvegicus    P17955
• Uncharacterized protein from Brain / Rattus norvegicus    
• Uncharacterized protein from Liver / Rattus norvegicus    
• Uncharacterized protein from Liver / Rattus norvegicus    

Source

• Liver (UBERON_0002107)   AH66-TC (CVCL_4368)   Plasma Membrane (GO_0005886)  
• Liver (UBERON_0002107)   BRL (CVCL_4565)   Nucleus (GO_0005634)  
• Liver (UBERON_0002107)   BTI-Tn-5B1-4 (CVCL_C190)  
• Liver (UBERON_0002107)   H5 (CVCL_4212)  
• Liver (UBERON_0002107)  
• Liver (UBERON_0002107)   Nucleus (GO_0005634)  

Reported structure

• O-Linked / Core 0 / GalNAc
• O-Linked / O-Fuc / Fuc
• O-Linked / O-GlcNAc / GlcNAc(b

Composition

• dHex:1 (avg mass : 164.1583 )
• HexNAc:1 (avg mass : 221.2103 )

Disease

• Carcinoma, Hepatocellular (DOID:684)
• Diabetes Mellitus, Non-insulin dependent (DOID:9352)

Reference

• O-GlcNAc Regulates FoxO Activation in Response to Glucose (2008 - Michael P Housley, Joseph T Rodgers, Namrata D Udeshi, Timothy J Kelly, Jeffrey Shabanowitz, Donald F Hunt, Pere Puigserver, Gerald W Hart) / Status : Reviewed
• C-mannosylation and O-fucosylation of the thrombospondin type 1 module. (2001 - Hofsteenge J, Huwiler K, Macek B, Hess D, Lawler J, Mosher D, Peter-Katalinic J) / Status : Reviewed
• Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine. (1987 - Holt G, Snow C, Senior A, Haltiwanger R, Gerace L, Hart G) / Status : Reviewed
• A nuclear specific glycoprotein representative of a unique pattern of glycosylation. (1987 - Schindler M, Hogan M, Miller R, DeGaetano D) / Status : Reviewed
• Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway. (1987 - Davis L, Blobel G) / Status : Reviewed
• Structure of O-glycosidically linked sugar units from plasma membranes of an ascites hepatoma, AH 66. (1982 - Funakoshi I, Yamashina I) / Status : Reviewed
• Characterization of novel amino acid fucosides. (1981 - Klinger M, Laine R, Steiner S) / Status : Reviewed

Reported glycosite

• Thrombospondin-1 / Homo sapiens
  •        Undefined site
  •        Thr-507
• Amino acid fucoside - fl3 / Rattus norvegicus
  •        Undefined site
• Nuclear pore glycoprotein p62 / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein from Brain / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein from Liver / Rattus norvegicus
  •        Undefined site
• Uncharacterized protein from Liver / Rattus norvegicus
  •        Undefined site

Mass spectrometry observed peptide

• STFRPRTSSNASTISGRLSP (20aa)
• PHTSGMNRL (9aa)
• FPHSVKTTTHSWVSG (15aa)